Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2008 1
2009 1
2010 1
2017 1
2018 3
2019 2
2020 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

10 results

Results by year

Filters applied: . Clear all
Page 1
Molecular analysis and prognostic impact of the novel apoptotic gene BCL2L12 in gastric cancer.
Florou D, Papadopoulos IN, Scorilas A. Florou D, et al. Biochem Biophys Res Commun. 2010 Jan 1;391(1):214-8. doi: 10.1016/j.bbrc.2009.11.034. Epub 2009 Nov 10. Biochem Biophys Res Commun. 2010. PMID: 19903463
BCL2L12 transcript was indicated in cancer gastric tissues to range from 29 to 53200 mRNA copies BCL2L12/10(6) mRNA copies GAPDH. Significant associations of BCL2L12 with gastric tumors of the early stages (I/II) (p=0.044) and of intestinal histotype ( …
BCL2L12 transcript was indicated in cancer gastric tissues to range from 29 to 53200 mRNA copies BCL2L12/10(6) mRNA copies GAP …
Bcl2L12 plays a critical role in the development of intestinal allergy.
Feng BS, Wu YJ, Hong JY, Geng XR, Liu JQ, Liu ZG, Zheng PY, Yang PC. Feng BS, et al. Immunol Lett. 2018 Nov;203:87-94. doi: 10.1016/j.imlet.2018.09.001. Epub 2018 Sep 5. Immunol Lett. 2018. PMID: 30194965
CD4(+) T cells from FA patients showed a Bcl2L12-dependent tendency to differentiate into Th2 cells. Bcl2L12 played a crucial role in induction of allergic response in the intestine. ...In conclusion, Bcl2L12 plays a crucial role in the induction of Th …
CD4(+) T cells from FA patients showed a Bcl2L12-dependent tendency to differentiate into Th2 cells. Bcl2L12 played a crucial …
Bcl2L12 Contributes to Th2-Biased Inflammation in the Intestinal Mucosa by Regulating CD4(+) T Cell Activities.
Li MG, Liu XY, Liu ZQ, Hong JY, Liu JQ, Zhou CJ, Hu TY, Xiao XJ, Ran PX, Zheng PY, Liu ZG, Yang PC. Li MG, et al. J Immunol. 2018 Jul 15;201(2):725-733. doi: 10.4049/jimmunol.1800139. Epub 2018 Jun 8. J Immunol. 2018. PMID: 29884701
Naive CD4(+) T cells with Bcl2L12 overexpression were prone to differentiate into Th2 cells. Mice with Bcl2L12 deficiency failed to induce the Th2-biased inflammation in the intestine. ...
Naive CD4(+) T cells with Bcl2L12 overexpression were prone to differentiate into Th2 cells. Mice with Bcl2L12 deficiency fail …
Bcl2L12 mediates effects of protease-activated receptor-2 on the pathogenesis of Th2-dominated responses of patients with ulcerative colitis.
Feng BS, Wu YJ, Zeng XH, Yu D, Liu ZQ, Zhou CJ, Liu ZG, Zheng PY, Yang PC. Feng BS, et al. Arch Biochem Biophys. 2018 Nov 1;657:8-14. doi: 10.1016/j.abb.2018.09.003. Epub 2018 Sep 11. Arch Biochem Biophys. 2018. PMID: 30217509
Activation of PAR2 increased expression of Bcl2L12 in CD4(+) T cells. Bcl2L12 mRNA decayed spontaneously in CD4(+) T cells after separated from UC patients which was prevented by activating PAR2. ...We conclude that CD4(+) T cells from UC patients expressed high lev …
Activation of PAR2 increased expression of Bcl2L12 in CD4(+) T cells. Bcl2L12 mRNA decayed spontaneously in CD4(+) T cells aft …
Molecular cloning, physical mapping, and expression analysis of a novel gene, BCL2L12, encoding a proline-rich protein with a highly conserved BH2 domain of the Bcl-2 family.
Scorilas A, Kyriakopoulou L, Yousef GM, Ashworth LK, Kwamie A, Diamandis EP. Scorilas A, et al. Genomics. 2001 Mar 1;72(2):217-21. doi: 10.1006/geno.2000.6455. Genomics. 2001. PMID: 11401436
BCL2L12 is expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. We also identified one splice variant of BCL2L12 that is prima …
BCL2L12 is expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, …
Quantitative expression analysis and prognostic significance of the novel apoptosis-related gene BCL2L12 in colon cancer.
Kontos CK, Papadopoulos IN, Scorilas A. Kontos CK, et al. Biol Chem. 2008 Dec;389(12):1467-75. doi: 10.1515/BC.2008.173. Biol Chem. 2008. PMID: 18844453
We have recently discovered and cloned a new member of the BCL2 gene family, BCL2L12, expressed in colon tissues. Here we have investigated expression of the BCL2L12 gene in colon cancer tissues and assessed its prognostic value. ...Our results suggest that BCL2L …
We have recently discovered and cloned a new member of the BCL2 gene family, BCL2L12, expressed in colon tissues. Here we have invest …
Regulating Bcl2L12 expression in mast cells inhibits food allergy.
Zheng PY, Geng XR, Hong JY, Yang G, Liu JQ, Mo LH, Feng Y, Zhang YY, Liu T, Ran P, Liu ZG, Yang PC. Zheng PY, et al. Theranostics. 2019 Jul 9;9(17):4982-4992. doi: 10.7150/thno.34001. eCollection 2019. Theranostics. 2019. PMID: 31410196 Free PMC article.
Inhibition of Bcl2L12 restored the apoptosis machinery of mast cells in the FA mouse intestine. Conclusions: The apoptosis machinery in mast cells is impaired in an allergic environment. Inhibition of Bcl2L12 restores the apoptosis machinery in mast cells in …
Inhibition of Bcl2L12 restored the apoptosis machinery of mast cells in the FA mouse intestine. Conclusions: The apoptosis mac …
Tumor necrosis factor suppresses interleukin 10 in peripheral B cells via upregulating Bcl2-like protein 12 in patients with inflammatory bowel disease.
Guo X, Li MG, Li SS, Liu FH, Liu ZJ, Yang PC. Guo X, et al. Cell Biochem Funct. 2017 Mar;35(2):77-82. doi: 10.1002/cbf.3250. Epub 2017 Jan 24. Cell Biochem Funct. 2017. PMID: 28120341
The IL-10 levels in B cells were negatively correlated with the expression of Bcl2L12. Exposure of B cells to TNF in the culture enhanced the expression of Bcl2L12. The Bcl2L12 mediated the effects of TNF on suppression of IL-10 in B cells. ...
The IL-10 levels in B cells were negatively correlated with the expression of Bcl2L12. Exposure of B cells to TNF in the culture enha …